PNAS: In a collaborative study, researchers led by RESOLV scientists, Prof. J. Tatzelt, Prof. K. Winklhofer, and Prof. R. Winter, have gained valuable insight into the development of prion diseases of the brain.
Chem. Eur. J.: Joint publication RESOLV members Prof. K. Morgenstern and Prof. W. Sander. It is well established that the confinement of reactants to two dimensions influences their reactivity. However, such confinement is often dominated by charge transfer effects between the reactants and the confining walls, in particular if the walls are conductive. Also, the reactivity of carbenes on metal…
JACS: Single-atom catalysts combine the advantages of homogeneous and heterogeneous catalysis. Researchers led by Prof. K. Exner have now shown that such structures can also be formed electrochemically – independently and without noble metals. They are highly selective and can be easily separated from the reaction mixture.
Prot. Sci.: Joint publication RESOLV members Prof. P. Petersen and Dr. A. V. Verde. Proteins of obligate halophilic organisms have an unusually high number of acidic amino acids, thought to enable them to function in multimolar KCl environments. Clarifying the molecular scale mechanisms by which this occurs is relevant for biotechnology, to enable enzymatic synthesis of economically important…
J. Mol. Biol.: Joint publication RESOLV members Prof. J. Tatzelt and Prof. K. F. Winklhofer. Several proteins associated with neurodegenerative diseases, such as the mammalian prion protein (PrP), undergo liquid–liquid phase separation (LLPS), which led to the hypothesis that condensates represent precursors in the formation of neurotoxic protein aggregates. However, the mechanisms that trigger…
J. Phys. Chem. Lett.: Joint publication RESOLV members Prof. D. Marx and Prof. J. Behler. Isotopic substitution, which can be realized in both experiment and computer simulations, is a direct approach to assess the role of nuclear quantum effects on the structure and dynamics of matter. However, the impact of nuclear quantum effects on the structure of liquid water as probed in experiment by…
Adv. Sci.: Researchers, led by RESOLV PI Prof. K. Tschulik published their findings. Covalent organic framework compounds are more active as catalysts than one would expect. Researchers have now discovered why.
JACS: RESOLV Principal Investigators Prof. G. Clever and Prof. L. Schäfer and their teams were able to show that social chiral self-sorting of coordination cages was dependent on specific solvent interactions.
Biophys. J.: Joint publication RESOLV members Prof. M. Havenith and Prof. R. Winter. In order to achieve a comprehensive understanding of protein aggregation processes, an exploration of solvation dynamics, a key yet intricate component of biological phenomena, is mandatory. In the present study, we used Fourier transform infrared spectroscopy and terahertz spectroscopy complemented by atomic…
